Cargando…
Deciphering the molecular basis for nucleotide selection by the West Nile virus RNA helicase
The West Nile virus RNA helicase uses the energy derived from the hydrolysis of nucleotides to separate complementary strands of RNA. Although this enzyme has a preference for ATP, the bias towards this purine nucleotide cannot be explained on the basis of specific protein–ATP interactions. Moreover...
Autores principales: | Despins, Simon, Issur, Moheshwarnath, Bougie, Isabelle, Bisaillon, Martin |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938200/ https://www.ncbi.nlm.nih.gov/pubmed/20421212 http://dx.doi.org/10.1093/nar/gkq276 |
Ejemplares similares
-
Nucleotide analogs and molecular modeling studies reveal key interactions involved in substrate recognition by the yeast RNA triphosphatase
por: Issur, Moheshwarnath, et al.
Publicado: (2009) -
Enzymatic Synthesis of RNAs Capped with Nucleotide Analogues Reveals the Molecular Basis for Substrate Selectivity of RNA Capping Enzyme: Impacts on RNA Metabolism
por: Issur, Moheshwarnath, et al.
Publicado: (2013) -
Observing inhibition of the SARS-CoV-2 helicase at single-nucleotide resolution
por: Marx, Sinduja K, et al.
Publicado: (2023) -
Molecular basis of nucleotide-dependent substrate engagement and remodeling by an AAA+ activator
por: Darbari, Vidya C., et al.
Publicado: (2014) -
The reverse gyrase helicase-like domain is a nucleotide-dependent switch that is attenuated by the topoisomerase domain
por: del Toro Duany, Yoandris, et al.
Publicado: (2008)