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PIAS1 regulates CP2c localization and active promoter complex formation in erythroid cell-specific α-globin expression

Data presented here extends our previous observations on α-globin transcriptional regulation by the CP2 and PIAS1 proteins. Using RNAi knockdown, we have now shown that CP2b, CP2c and PIAS1 are each necessary for synergistic activation of endogenous α-globin gene expression in differentiating MEL ce...

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Detalles Bibliográficos
Autores principales: Chul Kang, Ho, Hyung Chae, Ji, Jeon, Jinseon, Kim, Won, Hyun Ha, Dae, Ho Shin, June, Gil Kim, Chan, Geun Kim, Chul
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938217/
https://www.ncbi.nlm.nih.gov/pubmed/20421208
http://dx.doi.org/10.1093/nar/gkq286

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