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Single molecule analysis of combinatorial splicing
Alternative splicing creates diverse mRNA isoforms from single genes and thereby enhances complexity of transcript structure and of gene function. We describe a method called spliceotyping, which translates combinatorial mRNA splicing patterns along transcripts into a library of binary strings of nu...
Autores principales: | Conze, Tim, Göransson, Jenny, Razzaghian, Hamid Reza, Ericsson, Olle, Öberg, Daniel, Akusjärvi, Göran, Landegren, Ulf, Nilsson, Mats |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938221/ https://www.ncbi.nlm.nih.gov/pubmed/20587504 http://dx.doi.org/10.1093/nar/gkq581 |
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