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Molecular basis of chemosensitivity of platinum pre-treated ovarian cancer to chemotherapy

BACKGROUND: Ovarian cancer shows considerable heterogeneity in its sensitivity to chemotherapy both clinically and in vitro. This study tested the hypothesis that the molecular basis of this difference lies within the known resistance mechanisms inherent to these patients' tumours. METHODS: The...

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Detalles Bibliográficos
Autores principales: Glaysher, S, Gabriel, F G, Johnson, P, Polak, M, Knight, L A, Parker, K, Poole, M, Narayanan, A, Cree, I A
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938260/
https://www.ncbi.nlm.nih.gov/pubmed/20700122
http://dx.doi.org/10.1038/sj.bjc.6605817