Cargando…

Whole blood-derived miRNA profiles as potential new tools for ovarian cancer screening

BACKGROUND: Screening is an unsolved problem for ovarian cancer (OvCA). As late detection is equivalent to poor prognosis, we analysed whether OvCA patients show diagnostically meaningful microRNA (miRNA) patterns in blood cells. METHODS: Blood-borne whole miRNome profiles from 24 patients with OvCA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Häusler, S F M, Keller, A, Chandran, P A, Ziegler, K, Zipp, K, Heuer, S, Krockenberger, M, Engel, J B, Hönig, A, Scheffler, M, Dietl, J, Wischhusen, J
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2010
Materias:	Molecular Diagnostics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938264/ https://www.ncbi.nlm.nih.gov/pubmed/20683447 http://dx.doi.org/10.1038/sj.bjc.6605833

Ejemplares similares

Urinary TIMP-1 and MMP-2 levels detect the presence of pancreatic malignancies
por: Roy, R, et al.
Publicado: (2014)

Serum HE4 concentration differentiates malignant ovarian tumours from ovarian endometriotic cysts
por: Huhtinen, K, et al.
Publicado: (2009)

Circulating cell-free miRNAs as biomarker for triple-negative breast cancer
por: Shin, V Y, et al.
Publicado: (2015)

Overexpression of LASP-1 mediates migration and proliferation of human ovarian cancer cells and influences zyxin localisation
por: Grunewald, T G P, et al.
Publicado: (2007)

SV40 associated miRNAs are not detectable in mesotheliomas
por: Gee, G V, et al.
Publicado: (2010)

miRNA profiling in metastatic renal cell carcinoma reveals a tumour-suppressor effect for miR-215
por: White, N M A, et al.
Publicado: (2011)

Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo
por: Winsel, S, et al.
Publicado: (2014)

Circulating biomarkers for detection of ovarian cancer and predicting cancer outcomes
por: Shapira, I, et al.
Publicado: (2014)

Gene expression profiling of primary cultures of ovarian epithelial cells identifies novel molecular classifiers of ovarian cancer
por: Le Page, C, et al.
Publicado: (2006)

Identification of genes and pathways associated with cytotoxic T lymphocyte infiltration of serous ovarian cancer
por: Leffers, N, et al.
Publicado: (2010)

Targeting pancreatic and ovarian carcinomas using the auristatin-based anti-CD70 antibody–drug conjugate SGN-75
por: Ryan, M C, et al.
Publicado: (2010)

Androgen-related expression of G-proteins in ovarian cancer
por: Sheach, L A, et al.
Publicado: (2009)

Dysregulation of miR-106a and miR-591 confers paclitaxel resistance to ovarian cancer
por: Huh, J H, et al.
Publicado: (2013)

Factors influencing p53 expression in ovarian cancer as a biomarker of clinical outcome in multicentre studies
por: de Graeff, P, et al.
Publicado: (2006)

The ErbB signalling pathway: protein expression and prognostic value in epithelial ovarian cancer
por: de Graeff, P, et al.
Publicado: (2008)

The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro
por: O'Brien, P M, et al.
Publicado: (2008)

Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer
por: Frietsch, J J, et al.
Publicado: (2010)

Expression of Twist increases the risk for recurrence and for poor survival in epithelial ovarian carcinoma patients
por: Hosono, S, et al.
Publicado: (2007)

High-temperature-required protein A2 as a predictive marker for response to chemotherapy and prognosis in patients with high-grade serous ovarian cancers
por: Miyamoto, M, et al.
Publicado: (2015)

Ascitic complement system in ovarian cancer
por: Bjørge, L, et al.
Publicado: (2005)

Differential miRNA expression profiles in variants of papillary thyroid carcinoma and encapsulated follicular thyroid tumours
por: Sheu, S-Y, et al.
Publicado: (2010)

Elevated serum CXCL16 is an independent predictor of poor survival in ovarian cancer and may reflect pro-metastatic ADAM protease activity
por: Gooden, M J M, et al.
Publicado: (2014)

MUC4 activates HER2 signalling and enhances the motility of human ovarian cancer cells
por: Ponnusamy, M P, et al.
Publicado: (2008)

A distinct molecular profile associated with mucinous epithelial ovarian cancer
por: Heinzelmann-Schwarz, V A, et al.
Publicado: (2006)

Creation of immortalised epithelial cells from ovarian endometrioma
por: Bono, Y, et al.
Publicado: (2012)

Expression of lysophosphatidic acid acyltransferase beta (LPAAT-β) in ovarian carcinoma: correlation with tumour grading and prognosis
por: Niesporek, S, et al.
Publicado: (2005)

Identification of candidate circulating cisplatin-resistant biomarkers from epithelial ovarian carcinoma cell secretomes
por: Teng, P-N, et al.
Publicado: (2014)

Reduced expression of chemokine (C-C motif) ligand-2 (CCL2) in ovarian adenocarcinoma
por: Arnold, J M, et al.
Publicado: (2005)

The chemokine, CXCL12, is an independent predictor of poor survival in ovarian cancer
por: Popple, A, et al.
Publicado: (2012)

Role of lymphangiogenesis in epithelial ovarian cancer
por: Sundar, S S, et al.
Publicado: (2006)

Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial–mesenchymal transition in ovarian carcinomas
por: Colomiere, M, et al.
Publicado: (2009)

EpCAM is overexpressed in local and metastatic prostate cancer, suppressed by chemotherapy and modulated by MET-associated miRNA-200c/205
por: Massoner, P, et al.
Publicado: (2014)

Enhanced expression of peroxisome proliferator-activated receptor gamma in epithelial ovarian carcinoma
por: Zhang, G Y, et al.
Publicado: (2005)

Mammaglobin B (SCGB2A1) is a novel tumour antigen highly differentially expressed in all major histological types of ovarian cancer: implications for ovarian cancer immunotherapy
por: Bellone, S, et al.
Publicado: (2013)

IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer
por: Abiko, K, et al.
Publicado: (2015)

ASPM and microcephalin expression in epithelial ovarian cancer correlates with tumour grade and survival
por: Brüning-Richardson, A, et al.
Publicado: (2011)

Identification of differentially expressed genes according to chemosensitivity in advanced ovarian serous adenocarcinomas: expression of GRIA2 predicts better survival
por: Choi, C H, et al.
Publicado: (2012)

Tissue factor expression as a possible determinant of thromboembolism in ovarian cancer
por: Uno, K, et al.
Publicado: (2007)

HE4 and CA125 as a diagnostic test in ovarian cancer: prospective validation of the Risk of Ovarian Malignancy Algorithm
por: Van Gorp, T, et al.
Publicado: (2011)

Downregulation of miRNA-424: a sign of field cancerisation in clinically normal tongue adjacent to squamous cell carcinoma
por: Boldrup, L, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_i6k6i6pgk9rq99nsnk3i1pce99