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In situ quantification of HER2–protein tyrosine kinase 6 (PTK6) protein–protein complexes in paraffin sections from breast cancer tissues
BACKGROUND: Protein tyrosine kinase 6 (PTK6; breast tumour kinase) is overexpressed in up to 86% of the invasive breast cancers, and its association with the oncoprotein human epidermal growth factor receptor 2 (HER2) was shown in vitro by co-precipitation. Furthermore, expression of PTK6 in tumours...
Autores principales: | Aubele, M, Spears, M, Ludyga, N, Braselmann, H, Feuchtinger, A, Taylor, K J, Lindner, K, Auer, G, Stering, K, Höfler, H, Schmitt, M, Bartlett, J M S |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938265/ https://www.ncbi.nlm.nih.gov/pubmed/20700126 http://dx.doi.org/10.1038/sj.bjc.6605836 |
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