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Lacosamide for the prevention of partial onset seizures in epileptic adults

Lacosamide is a newly registered antiepileptic drug with dual mechanisms of action. It selectively enhances slow inactivation of voltage-gated sodium channels, resulting in stabilization of hyperexcitable neuronal membranes and inhibition of repetitive neuronal firing. It also binds to a collapsing-...

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Detalles Bibliográficos
Autores principales: Kelemen, Anna, Halász, Péter
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938295/
https://www.ncbi.nlm.nih.gov/pubmed/20856610