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Complex I-Associated Hydrogen Peroxide Production Is Decreased and Electron Transport Chain Enzyme Activities Are Altered in n-3 Enriched fat-1 Mice

The polyunsaturated nature of n-3 fatty acids makes them prone to oxidative damage. However, it is not clear if n-3 fatty acids are simply a passive site for oxidative attack or if they also modulate mitochondrial reactive oxygen species (ROS) production. The present study used fat-1 transgenic mice...

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Detalles Bibliográficos
Autores principales: Hagopian, Kevork, Weber, Kristina L., Hwee, Darren T., Van Eenennaam, Alison L., López-Lluch, Guillermo, Villalba, José M., Burón, Isabel, Navas, Plácido, German, J. Bruce, Watkins, Steven M., Chen, Yana, Wei, Alfreda, McDonald, Roger B., Ramsey, Jon J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938348/
https://www.ncbi.nlm.nih.gov/pubmed/20856881
http://dx.doi.org/10.1371/journal.pone.0012696