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Ubc4 and Not4 Regulate Steady-State Levels of DNA Polymerase-α to Promote Efficient and Accurate DNA Replication

The accurate duplication of chromosomal DNA is required to maintain genomic integrity. However, from an evolutionary point of view, a low mutation rate during DNA replication is desirable. One way to strike the right balance between accuracy and limited mutagenesis is to use a DNA polymerase that la...

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Detalles Bibliográficos
Autores principales: Haworth, Justin, Alver, Robert C., Anderson, Melissa, Bielinsky, Anja-Katrin
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938386/
https://www.ncbi.nlm.nih.gov/pubmed/20660159
http://dx.doi.org/10.1091/mbc.E09-06-0452