A Phosphatidylinositol 3-Kinase/Protein Kinase B-independent Activation of Mammalian Target of Rapamycin Signaling Is Sufficient to Induce Skeletal Muscle Hypertrophy

It has been widely proposed that signaling by mammalian target of rapamycin (mTOR) is both necessary and sufficient for the induction of skeletal muscle hypertrophy. Evidence for this hypothesis is largely based on studies that used stimuli that activate mTOR via a phosphatidylinositol 3-kinase (PI3...

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Detalles Bibliográficos
Autores principales: Goodman, Craig A., Miu, Man Hing, Frey, John W., Mabrey, Danielle M., Lincoln, Hannah C., Ge, Yejing, Chen, Jie, Hornberger, Troy A.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938390/
https://www.ncbi.nlm.nih.gov/pubmed/20668162
http://dx.doi.org/10.1091/mbc.E10-05-0454

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