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Modeling of Tau-Mediated Synaptic and Neuronal Degeneration in Alzheimer's Disease
Patients suffering from Alzheimer's disease (AD) are typified and diagnosed postmortem by the combined accumulations of extracellular amyloid plaques and of intracellular tauopathy, consisting of neuropil treads and neurofibrillary tangles in the somata. Both hallmarks are inseparable and remai...
Autores principales: | Jaworski, Tomasz, Kügler, Sebastian, Van Leuven, Fred |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
SAGE-Hindawi Access to Research
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938448/ https://www.ncbi.nlm.nih.gov/pubmed/20862366 http://dx.doi.org/10.4061/2010/573138 |
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