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SIRT1 decreases Lox-1-mediated foam cell formation in atherogenesis

AIMS: Endothelial activation, macrophage infiltration, and foam cell formation are pivotal steps in atherogenesis. Our aim in this study was to analyse the role of SIRT1, a class III deacetylase with important metabolic functions, in plaque macrophages and atherogenesis. METHODS AND RESULTS: Using p...

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Detalles Bibliográficos
Autores principales:	Stein, Sokrates, Lohmann, Christine, Schäfer, Nicola, Hofmann, Janin, Rohrer, Lucia, Besler, Christian, Rothgiesser, Karin M., Becher, Burkhard, Hottiger, Michael O., Borén, Jan, McBurney, Michael W., Landmesser, Ulf, Lüscher, Thomas F., Matter, Christian M.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Basic Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938465/ https://www.ncbi.nlm.nih.gov/pubmed/20418343 http://dx.doi.org/10.1093/eurheartj/ehq107

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