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Autophagy, a guardian against neurodegeneration
Autophagy is an intracellular degradation process responsible for the clearance of most long-lived proteins and organelles. Cytoplasmic components are enclosed by double-membrane autophagosomes, which subsequently fuse with lysosomes for degradation. Autophagy dysfunction may contribute to the patho...
Autores principales: | García-Arencibia, Moisés, Hochfeld, Warren E., Toh, Pearl P.C., Rubinsztein, David C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938570/ https://www.ncbi.nlm.nih.gov/pubmed/20188203 http://dx.doi.org/10.1016/j.semcdb.2010.02.008 |
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