Role for PKC δ in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells

The synthetic Vitamin A analog fenretinide is a promising chemotherapeutic agent. In the current paper, the role of PKC δ was examined in fenretinide-induced apoptosis in lymphoid leukemia cells. Levels of proapoptotic cleaved PKC δ positively correlated with drug sensitivity. Fenretinide promoted r...

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Detalles Bibliográficos
Autores principales: Ruvolo, Vivian R., Karanjeet, Kul B., Schuster, Todd F., Brown, Rhoderick, Deng, Yibin, Hinchcliffe, Edward, Ruvolo, Peter P.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938797/
https://www.ncbi.nlm.nih.gov/pubmed/20844597
http://dx.doi.org/10.1155/2010/584657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938797/
https://www.ncbi.nlm.nih.gov/pubmed/20844597
http://dx.doi.org/10.1155/2010/584657

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