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Role for PKC δ in Fenretinide-Mediated Apoptosis in Lymphoid Leukemia Cells

The synthetic Vitamin A analog fenretinide is a promising chemotherapeutic agent. In the current paper, the role of PKC δ was examined in fenretinide-induced apoptosis in lymphoid leukemia cells. Levels of proapoptotic cleaved PKC δ positively correlated with drug sensitivity. Fenretinide promoted r...

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Detalles Bibliográficos
Autores principales:	Ruvolo, Vivian R., Karanjeet, Kul B., Schuster, Todd F., Brown, Rhoderick, Deng, Yibin, Hinchcliffe, Edward, Ruvolo, Peter P.
Formato:	Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938797/ https://www.ncbi.nlm.nih.gov/pubmed/20844597 http://dx.doi.org/10.1155/2010/584657

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