Comparisons between Chemical Mapping and Binding to Isoenergetic Oligonucleotide Microarrays Reveal Unexpected Patterns of Binding to the Bacillus subtilis RNase P RNA Specificity Domain

[Image: see text] Microarrays with isoenergetic pentamer and hexamer 2′-O-methyl oligonucleotide probes with LNA (locked nucleic acid) and 2,6-diaminopurine substitutions were used to probe the binding sites on the RNase P RNA specificity domain of Bacillus subtilis. Unexpected binding patterns were...

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Detalles Bibliográficos
Autores principales: Liang, Ruiting, Kierzek, Elzbieta, Kierzek, Ryszard, Turner, Douglas H.
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society 2010
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2938832/
https://www.ncbi.nlm.nih.gov/pubmed/20557101
http://dx.doi.org/10.1021/bi100286n

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