Hybrid Molecular Structure of the Giant Protease Tripeptidyl Peptidase II

Tripeptidyl peptidase II (TPP II) is the largest known eukaryotic protease (6MDa). It is believed to act downstream of the 26S proteasome cleaving tripeptides from the N– termini of longer peptides and it is implicated in numerous cellular processes. Here we report the structure of Drosophila TPP II...

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Detalles Bibliográficos
Autores principales: Chuang, Crystal K., Rockel, Beate, Seyit, Gönül, Walian, Peter J., Schönegge, Anne–Marie, Peters, Jürgen, Zwart, Petrus H., Baumeister, Wolfgang, Jap, Bing K.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939011/
https://www.ncbi.nlm.nih.gov/pubmed/20676100
http://dx.doi.org/10.1038/nsmb.1870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939011/
https://www.ncbi.nlm.nih.gov/pubmed/20676100
http://dx.doi.org/10.1038/nsmb.1870

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