The Unfolded Protein Response Is Not Necessary for the G1/S Transition, but It Is Required for Chromosome Maintenance in Saccharomyces cerevisiae

BACKGROUND: The unfolded protein response (UPR) is a eukaryotic signaling pathway, from the endoplasmic reticulum (ER) to the nucleus. Protein misfolding in the ER triggers the UPR. Accumulating evidence links the UPR in diverse aspects of cellular homeostasis. The UPR responds to the overall protei...

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Detalles Bibliográficos
Autores principales: Henry, Kelsey A., Blank, Heidi M., Hoose, Scott A., Polymenis, Michael
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939067/
https://www.ncbi.nlm.nih.gov/pubmed/20856872
http://dx.doi.org/10.1371/journal.pone.0012732

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