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A biopsy sample reduction approach to identify significant alterations of the testicular transcriptome in the presence of Y-chromosomal microdeletions that are independent of germ cell composition

Y-chromosomal microdeletions (YCMD) are the major genetic cause of male infertility. To date, it is not known which global changes are induced by the presence of AZFc or AZFb + c deletions in the human testicular transcriptome. We investigated this question by microarray analysis in which we had to...

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Detalles Bibliográficos
Autores principales: Cappallo-Obermann, Heike, von Kopylow, Kathrein, Schulze, Wolfgang, Spiess, Andrej-Nikolai
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939328/
https://www.ncbi.nlm.nih.gov/pubmed/20668881
http://dx.doi.org/10.1007/s00439-010-0865-9

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