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A biopsy sample reduction approach to identify significant alterations of the testicular transcriptome in the presence of Y-chromosomal microdeletions that are independent of germ cell composition
Y-chromosomal microdeletions (YCMD) are the major genetic cause of male infertility. To date, it is not known which global changes are induced by the presence of AZFc or AZFb + c deletions in the human testicular transcriptome. We investigated this question by microarray analysis in which we had to...
Autores principales: | Cappallo-Obermann, Heike, von Kopylow, Kathrein, Schulze, Wolfgang, Spiess, Andrej-Nikolai |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939328/ https://www.ncbi.nlm.nih.gov/pubmed/20668881 http://dx.doi.org/10.1007/s00439-010-0865-9 |
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