Heterogeneity of IL-22-producing Lymphoid Tissue Inducer-like Cells in Human and Mouse

Lymphoid tissue inducer (LTi) cells have been characterized in mouse as a key cell when secondary lymphoid tissues are organized during development and memory T cells are formed after birth. In addition to their involvement in adaptive immune responses, recent studies show that they contribute to in...

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Detalles Bibliográficos
Autores principales: Kim, Soochan, Han, Sinsuk, Kim, Mi-Yeon
Formato: Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2010
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939355/
https://www.ncbi.nlm.nih.gov/pubmed/20844735
http://dx.doi.org/10.4110/in.2010.10.4.115
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author Kim, Soochan
Han, Sinsuk
Kim, Mi-Yeon
author_facet Kim, Soochan
Han, Sinsuk
Kim, Mi-Yeon
author_sort Kim, Soochan
collection PubMed
description Lymphoid tissue inducer (LTi) cells have been characterized in mouse as a key cell when secondary lymphoid tissues are organized during development and memory T cells are formed after birth. In addition to their involvement in adaptive immune responses, recent studies show that they contribute to innate immune responses by producing large amount of interleukin (IL)-22 against microbial attack. Here, we compare IL-22-producing LTi and LTi-like cells in human and mouse and discuss their heterogeneity in different tissues.
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spelling pubmed-29393552010-09-15 Heterogeneity of IL-22-producing Lymphoid Tissue Inducer-like Cells in Human and Mouse Kim, Soochan Han, Sinsuk Kim, Mi-Yeon Immune Netw Review Article Lymphoid tissue inducer (LTi) cells have been characterized in mouse as a key cell when secondary lymphoid tissues are organized during development and memory T cells are formed after birth. In addition to their involvement in adaptive immune responses, recent studies show that they contribute to innate immune responses by producing large amount of interleukin (IL)-22 against microbial attack. Here, we compare IL-22-producing LTi and LTi-like cells in human and mouse and discuss their heterogeneity in different tissues. The Korean Association of Immunologists 2010-08 2010-08-31 /pmc/articles/PMC2939355/ /pubmed/20844735 http://dx.doi.org/10.4110/in.2010.10.4.115 Text en Copyright © 2010 The Korean Association of Immunologists http://creativecommons.org/licenses/by-nc/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kim, Soochan
Han, Sinsuk
Kim, Mi-Yeon
Heterogeneity of IL-22-producing Lymphoid Tissue Inducer-like Cells in Human and Mouse
title Heterogeneity of IL-22-producing Lymphoid Tissue Inducer-like Cells in Human and Mouse
title_full Heterogeneity of IL-22-producing Lymphoid Tissue Inducer-like Cells in Human and Mouse
title_fullStr Heterogeneity of IL-22-producing Lymphoid Tissue Inducer-like Cells in Human and Mouse
title_full_unstemmed Heterogeneity of IL-22-producing Lymphoid Tissue Inducer-like Cells in Human and Mouse
title_short Heterogeneity of IL-22-producing Lymphoid Tissue Inducer-like Cells in Human and Mouse
title_sort heterogeneity of il-22-producing lymphoid tissue inducer-like cells in human and mouse
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939355/
https://www.ncbi.nlm.nih.gov/pubmed/20844735
http://dx.doi.org/10.4110/in.2010.10.4.115
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AT hansinsuk heterogeneityofil22producinglymphoidtissueinducerlikecellsinhumanandmouse
AT kimmiyeon heterogeneityofil22producinglymphoidtissueinducerlikecellsinhumanandmouse

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