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IGF1 activates cell cycle arrest following irradiation by reducing binding of ΔNp63 to the p21 promoter
Radiotherapy for head and neck tumors often results in persistent loss of function in salivary glands. Patients suffering from impaired salivary function frequently terminate treatment prematurely because of reduced quality of life caused by malnutrition and other debilitating side-effects. It has b...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939491/ https://www.ncbi.nlm.nih.gov/pubmed/21480565 http://dx.doi.org/10.1038/cddis.2010.28 |