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A haplotype inference algorithm for trios based on deterministic sampling

BACKGROUND: In genome-wide association studies, thousands of individuals are genotyped in hundreds of thousands of single nucleotide polymorphisms (SNPs). Statistical power can be increased when haplotypes, rather than three-valued genotypes, are used in analysis, so the problem of haplotype phase i...

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Detalles Bibliográficos
Autores principales: Iliadis, Alexandros, Watkinson, John, Anastassiou, Dimitris, Wang, Xiaodong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939632/
https://www.ncbi.nlm.nih.gov/pubmed/20727218
http://dx.doi.org/10.1186/1471-2156-11-78