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A haplotype inference algorithm for trios based on deterministic sampling
BACKGROUND: In genome-wide association studies, thousands of individuals are genotyped in hundreds of thousands of single nucleotide polymorphisms (SNPs). Statistical power can be increased when haplotypes, rather than three-valued genotypes, are used in analysis, so the problem of haplotype phase i...
Autores principales: | Iliadis, Alexandros, Watkinson, John, Anastassiou, Dimitris, Wang, Xiaodong |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939632/ https://www.ncbi.nlm.nih.gov/pubmed/20727218 http://dx.doi.org/10.1186/1471-2156-11-78 |
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