Cargando…

Dendritic Cell-Specific Antigen Delivery by Coronavirus Vaccine Vectors Induces Long-Lasting Protective Antiviral and Antitumor Immunity

Efficient vaccination against infectious agents and tumors depends on specific antigen targeting to dendritic cells (DCs). We report here that biosafe coronavirus-based vaccine vectors facilitate delivery of multiple antigens and immunostimulatory cytokines to professional antigen-presenting cells i...

Descripción completa

Detalles Bibliográficos
Autores principales: Cervantes-Barragan, Luisa, Züst, Roland, Maier, Reinhard, Sierro, Sophie, Janda, Jozef, Levy, Frederic, Speiser, Daniel, Romero, Pedro, Rohrlich, Pierre-Simon, Ludewig, Burkhard, Thiel, Volker
Formato: Texto
Lenguaje:English
Publicado: American Society of Microbiology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939679/
https://www.ncbi.nlm.nih.gov/pubmed/20844609
http://dx.doi.org/10.1128/mBio.00171-10