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Deficiency of the Metalloproteinase-Disintegrin ADAM8 Is Associated with Thymic Hyper-Cellularity
BACKGROUND: Thymopoiesis requires thymocyte-stroma interactions and proteases that promote cell migration by degrading extracellular matrix and releasing essential cytokines and chemokines. A role for several members of the A Disintegrin and Metalloprotease (ADAM) family in T cell development has be...
Autores principales: | Gossens, Klaus, Naus, Silvia, Holländer, Georg A., Ziltener, Hermann J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939894/ https://www.ncbi.nlm.nih.gov/pubmed/20856819 http://dx.doi.org/10.1371/journal.pone.0012766 |
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