The role of proteomics in depression research

Depression is a severe neuropsychiatric disorder affecting approximately 10% of the world population. Despite this, the molecular mechanisms underlying the disorder are still not understood. Novel technologies such as proteomic-based platforms are beginning to offer new insights into this devastatin...

Descripción completa

Detalles Bibliográficos
Autores principales: Martins-de-Souza, Daniel, Harris, Laura W., Guest, Paul C., Turck, Christoph W., Bahn, Sabine
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940035/
https://www.ncbi.nlm.nih.gov/pubmed/19997739
http://dx.doi.org/10.1007/s00406-009-0093-2
_version_ 1782186791756890112
author Martins-de-Souza, Daniel
Harris, Laura W.
Guest, Paul C.
Turck, Christoph W.
Bahn, Sabine
author_facet Martins-de-Souza, Daniel
Harris, Laura W.
Guest, Paul C.
Turck, Christoph W.
Bahn, Sabine
author_sort Martins-de-Souza, Daniel
collection PubMed
description Depression is a severe neuropsychiatric disorder affecting approximately 10% of the world population. Despite this, the molecular mechanisms underlying the disorder are still not understood. Novel technologies such as proteomic-based platforms are beginning to offer new insights into this devastating illness, beyond those provided by the standard targeted methodologies. Here, we will show the potential of proteome analyses as a tool to elucidate the pathophysiological mechanisms of depression as well as the discovery of potential diagnostic, therapeutic and disease course biomarkers.
format Text
id pubmed-2940035
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher Springer-Verlag
record_format MEDLINE/PubMed
spelling pubmed-29400352010-10-05 The role of proteomics in depression research Martins-de-Souza, Daniel Harris, Laura W. Guest, Paul C. Turck, Christoph W. Bahn, Sabine Eur Arch Psychiatry Clin Neurosci Original Paper Depression is a severe neuropsychiatric disorder affecting approximately 10% of the world population. Despite this, the molecular mechanisms underlying the disorder are still not understood. Novel technologies such as proteomic-based platforms are beginning to offer new insights into this devastating illness, beyond those provided by the standard targeted methodologies. Here, we will show the potential of proteome analyses as a tool to elucidate the pathophysiological mechanisms of depression as well as the discovery of potential diagnostic, therapeutic and disease course biomarkers. Springer-Verlag 2009-12-09 2010 /pmc/articles/PMC2940035/ /pubmed/19997739 http://dx.doi.org/10.1007/s00406-009-0093-2 Text en © The Author(s) 2009 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Original Paper
Martins-de-Souza, Daniel
Harris, Laura W.
Guest, Paul C.
Turck, Christoph W.
Bahn, Sabine
The role of proteomics in depression research
title The role of proteomics in depression research
title_full The role of proteomics in depression research
title_fullStr The role of proteomics in depression research
title_full_unstemmed The role of proteomics in depression research
title_short The role of proteomics in depression research
title_sort role of proteomics in depression research
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940035/
https://www.ncbi.nlm.nih.gov/pubmed/19997739
http://dx.doi.org/10.1007/s00406-009-0093-2
work_keys_str_mv AT martinsdesouzadaniel theroleofproteomicsindepressionresearch
AT harrislauraw theroleofproteomicsindepressionresearch
AT guestpaulc theroleofproteomicsindepressionresearch
AT turckchristophw theroleofproteomicsindepressionresearch
AT bahnsabine theroleofproteomicsindepressionresearch
AT martinsdesouzadaniel roleofproteomicsindepressionresearch
AT harrislauraw roleofproteomicsindepressionresearch
AT guestpaulc roleofproteomicsindepressionresearch
AT turckchristophw roleofproteomicsindepressionresearch
AT bahnsabine roleofproteomicsindepressionresearch

Ejemplares similares