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Single-molecule dynamics of gating in a neurotransmitter transporter homolog
Neurotransmitter:Na(+) symporters (NSS) remove neurotransmitters from the synapse in a reuptake process driven by the Na(+) gradient. Drugs that interfere with this reuptake mechanism, such as cocaine and antidepressants, profoundly influence behavior and mood. In order to probe the nature of confor...
Autores principales: | Zhao, Yongfang, Terry, Daniel, Shi, Lei, Weinstein, Harel, Blanchard, Scott C., Javitch, Jonathan A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940119/ https://www.ncbi.nlm.nih.gov/pubmed/20463731 http://dx.doi.org/10.1038/nature09057 |
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