Tumor Gene Expression Profiling in Women with Breast Cancer: Test Category: Prognostic

Differences in the expression of specific genes within breast tumors have been associated with risk of recurrence after treatment. Most women with Stage I or II node-negative breast cancer (especially when estrogen-receptor positive and treated with tamoxifen) remain disease-free at 10 years. Inform...

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Detalles Bibliográficos
Autores principales: Bellcross, Cecelia, W. David Dotson
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Evidence on Genomic Tests
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940139/
https://www.ncbi.nlm.nih.gov/pubmed/20877449
http://dx.doi.org/10.1371/currents.RRN1178
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author Bellcross, Cecelia
W. David Dotson,
author_facet Bellcross, Cecelia
W. David Dotson,
author_sort Bellcross, Cecelia
collection PubMed
description Differences in the expression of specific genes within breast tumors have been associated with risk of recurrence after treatment. Most women with Stage I or II node-negative breast cancer (especially when estrogen-receptor positive and treated with tamoxifen) remain disease-free at 10 years. Information on risk of recurrence could help identify women most likely to benefit from chemotherapy. Several clinically available gene expression profiles (GEP) provide “recurrence risk scores” that are intended to supplement information used by clinicians and patients in treatment decision-making.
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spelling pubmed-29401392010-09-28 Tumor Gene Expression Profiling in Women with Breast Cancer: Test Category: Prognostic Bellcross, Cecelia W. David Dotson, PLoS Curr Evidence on Genomic Tests Differences in the expression of specific genes within breast tumors have been associated with risk of recurrence after treatment. Most women with Stage I or II node-negative breast cancer (especially when estrogen-receptor positive and treated with tamoxifen) remain disease-free at 10 years. Information on risk of recurrence could help identify women most likely to benefit from chemotherapy. Several clinically available gene expression profiles (GEP) provide “recurrence risk scores” that are intended to supplement information used by clinicians and patients in treatment decision-making. Public Library of Science 2010-09-02 /pmc/articles/PMC2940139/ /pubmed/20877449 http://dx.doi.org/10.1371/currents.RRN1178 Text en http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Evidence on Genomic Tests
Bellcross, Cecelia
W. David Dotson,
Tumor Gene Expression Profiling in Women with Breast Cancer: Test Category: Prognostic
title Tumor Gene Expression Profiling in Women with Breast Cancer: Test Category: Prognostic
title_full Tumor Gene Expression Profiling in Women with Breast Cancer: Test Category: Prognostic
title_fullStr Tumor Gene Expression Profiling in Women with Breast Cancer: Test Category: Prognostic
title_full_unstemmed Tumor Gene Expression Profiling in Women with Breast Cancer: Test Category: Prognostic
title_short Tumor Gene Expression Profiling in Women with Breast Cancer: Test Category: Prognostic
title_sort tumor gene expression profiling in women with breast cancer: test category: prognostic
topic Evidence on Genomic Tests
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940139/
https://www.ncbi.nlm.nih.gov/pubmed/20877449
http://dx.doi.org/10.1371/currents.RRN1178
work_keys_str_mv AT bellcrosscecelia tumorgeneexpressionprofilinginwomenwithbreastcancertestcategoryprognostic
AT wdaviddotson tumorgeneexpressionprofilinginwomenwithbreastcancertestcategoryprognostic

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