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Role of the complement components C5 and C3a in a mouse model of myocardial ischemia and reperfusion injury
Objective: Ischemic heart disease is the leading cause of death worldwide. The complement system plays a major role in inflammation and tissue injury following myocardial ischemia and reperfusion (MI/R) injury. Systemic C5 inhibition in clinical studies has resulted in mixed results and the role of...
Autores principales: | Busche, Marc N., Stahl, Gregory L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
German Medical Science GMS Publishing House
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940219/ https://www.ncbi.nlm.nih.gov/pubmed/20930931 http://dx.doi.org/10.3205/000109 |
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