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Evaluating reproducibility of differential expression discoveries in microarray studies by considering correlated molecular changes

Motivation: According to current consistency metrics such as percentage of overlapping genes (POG), lists of differentially expressed genes (DEGs) detected from different microarray studies for a complex disease are often highly inconsistent. This irreproducibility problem also exists in other high-...

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Detalles Bibliográficos
Autores principales: Zhang, Min, Zhang, Lin, Zou, Jinfeng, Yao, Chen, Xiao, Hui, Liu, Qing, Wang, Jing, Wang, Dong, Wang, Chenguang, Guo, Zheng
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940240/
https://www.ncbi.nlm.nih.gov/pubmed/19417058
http://dx.doi.org/10.1093/bioinformatics/btp295