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Chloroquine activates the p53 pathway and induces apoptosis in human glioma cells
Glioblastoma is the most common malignant brain tumor in adults. The currently available treatments offer only a palliative survival advantage and the need for effective treatments remains an urgent priority. Activation of the p53 growth suppression/apoptotic pathway is one of the promising strategi...
Autores principales: | Kim, Ella L., Wüstenberg, Robin, Rübsam, Anne, Schmitz-Salue, Christoph, Warnecke, Gabriele, Bücker, Eva-Maria, Pettkus, Nadine, Speidel, Daniel, Rohde, Veit, Schulz-Schaeffer, Walter, Deppert, Wolfgang, Giese, Alf |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940600/ https://www.ncbi.nlm.nih.gov/pubmed/20308316 http://dx.doi.org/10.1093/neuonc/nop046 |
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