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Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers
BACKGROUND: Genomic gains and losses are a result of genomic instability in many types of cancers. BRCA1- and BRCA2-mutated breast cancers are associated with increased amounts of chromosomal aberrations, presumably due their functions in genome repair. Some of these genomic aberrations may harbor g...
Autores principales: | Holstege, Henne, van Beers, Erik, Velds, Arno, Liu, Xiaoling, Joosse, Simon A, Klarenbeek, Sjoerd, Schut, Eva, Kerkhoven, Ron, Klijn, Christiaan N, Wessels, Lodewyk FA, Nederlof, Petra M, Jonkers, Jos |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940799/ https://www.ncbi.nlm.nih.gov/pubmed/20735817 http://dx.doi.org/10.1186/1471-2407-10-455 |
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