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Inhibitory effects on HAV IRES-mediated translation and replication by a combination of amantadine and interferon-alpha
Hepatitis A virus (HAV) causes acute hepatitis and sometimes leads to fulminant hepatitis. Amantadine is a tricyclic symmetric amine that inhibits the replication of many DNA and RNA viruses. Amantadine was reported to suppress HAV replication, and the efficacy of amantadine was exhibited in its inh...
| Autores principales: | , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940810/ https://www.ncbi.nlm.nih.gov/pubmed/20815893 http://dx.doi.org/10.1186/1743-422X-7-212 |