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I-kappa-kinase-2 (IKK-2) inhibition potentiates vincristine cytotoxicity in non-Hodgkin's lymphoma

BACKGROUND: IKK-2 is an important regulator of the nuclear factor-κB (NF-κB) which has been implicated in survival, proliferation and apoptosis resistance of lymphoma cells. In this study, we investigated whether inhibition of IKK-2 impacts cell growth or cytotoxicity of selected conventional chemot...

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Detalles Bibliográficos
Autores principales:	Al-Katib, Ayad, Arnold, Alan A, Aboukameel, Amro, Sosin, Angela, Smith, Peter, Mohamed, Anwar N, Beck, Frances W, Mohammad, Ramzi M
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940845/ https://www.ncbi.nlm.nih.gov/pubmed/20809973 http://dx.doi.org/10.1186/1476-4598-9-228

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