Cargando…

A comprehensive platform for quality control of botanical drugs (PhytomicsQC): a case study of Huangqin Tang (HQT) and PHY906

BACKGROUND: Establishing botanical extracts as globally-accepted polychemical medicines and a new paradigm for disease treatment, requires the development of high-level quality control metrics. Based on comprehensive chemical and biological fingerprints correlated with pharmacology, we propose a gen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tilton, Robert, Paiva, Anthony A, Guan, Jing-Qu, Marathe, Rajendra, Jiang, Zaoli, van Eyndhoven, Winfried, Bjoraker, Jeffrey, Prusoff, Zachary, Wang, Hailong, Liu, Shwu-Huey, Cheng, Yung-Chi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940884/ https://www.ncbi.nlm.nih.gov/pubmed/20727161 http://dx.doi.org/10.1186/1749-8546-5-30

Ejemplares similares

Mechanism Based Quality Control (MBQC) of Herbal Products: A Case Study YIV-906 (PHY906)
por: Lam, Wing, et al.
Publicado: (2018)

Research on the Protective Effect of MiR-185-3p Mediated by Huangqin-Tang Decoction (HQT) on the Epithelial Barrier Function of Ulcerative Colitis
por: Changlin, Zhou, et al.
Publicado: (2021)

The number of intestinal bacteria is not critical for the enhancement of antitumor activity and reduction of intestinal toxicity of irinotecan by the Chinese herbal medicine PHY906 (KD018)
por: Lam, Wing, et al.
Publicado: (2014)

Huangqin-Tang and Ingredients in Modulating the Pathogenesis of Ulcerative Colitis
por: Wang, Chunyan, et al.
Publicado: (2017)

PHY906(KD018), an adjuvant based on a 1800-year-old Chinese medicine, enhanced the anti-tumor activity of Sorafenib by changing the tumor microenvironment
por: Lam, Wing, et al.
Publicado: (2015)

Effect of Huangqin Tang on Colonic Gene Expression in Rats with Ulcerative Colitis
por: Wang, Dunfang, et al.
Publicado: (2020)

Interaction of a traditional Chinese Medicine (PHY906) and CPT-11 on the inflammatory process in the tumor microenvironment
por: Wang, Ena, et al.
Publicado: (2011)

A Phase II Clinical Trial on the Combination Therapy of PHY906 Plus Capecitabine in Hepatocellular Carcinoma
por: Changou, Chun A., et al.
Publicado: (2020)

Systematic Evaluation of Randomized Clinical Trials of Huangqin Tang in Combination with Mesalazine for Ulcerative Colitis
por: Pan, Chengyu, et al.
Publicado: (2022)

Huangqin-Tang Ameliorates TNBS-Induced Colitis by Regulating Effector and Regulatory CD4(+) T Cells
por: Zou, Ying, et al.
Publicado: (2015)

Exploring the metabolic and physiological roles of HQT in S. lycopersicum by gene editing
por: D’Orso, Fabio, et al.
Publicado: (2023)

Phytome: a platform for plant comparative genomics
por: Hartmann, Stefanie, et al.
Publicado: (2006)

The Significant Pathways and Genes Underlying the Colon Cancer Treatment by the Traditional Chinese Medicine PHY906
por: Su, Ziyuan, et al.
Publicado: (2017)

Flavonoid profiling of a traditional Chinese medicine formula of Huangqin Tang using high performance liquid chromatography
por: Li, Tao, et al.
Publicado: (2016)

Huangqin Tang Interference With Colitis Associated Colorectal Cancer Through Regulation of Epithelial Mesenchymal Transition and Cell Cycle
por: Ma, Xuran, et al.
Publicado: (2022)

Radix Scutellariae — Huangqin
por: Wagner, Hildebert, et al.
Publicado: (2011)

Effect of Huangqin Tang on Urine Metabolic Profile in Rats with Ulcerative Colitis Based on UPLC-Q-Exactive Orbitrap MS
por: Wang, Dunfang, et al.
Publicado: (2020)

Transcriptomics and experimental validation-based approach to understand the effect and mechanism of Huangqin tang interfeience with colitis associated colorectal cancer
por: Ma, Xuran, et al.
Publicado: (2023)

Huangqin-tang ameliorates dextran sodium sulphate-induced colitis by regulating intestinal epithelial cell homeostasis, inflammation and immune response
por: Zou, Ying, et al.
Publicado: (2016)

WGCNA reveals key gene modules regulated by the combined treatment of colon cancer with PHY906 and CPT11
por: Xing, Shuqin, et al.
Publicado: (2020)

YIV-906 potentiated anti-PD1 action against hepatocellular carcinoma by enhancing adaptive and innate immunity in the tumor microenvironment
por: Yang, Xiaochen, et al.
Publicado: (2021)

3D phytomer-based geometric modelling method for plants—the case of maize
por: Wen, Weiliang, et al.
Publicado: (2021)

Correlation of the temporal and spatial expression patterns of HQT with the biosynthesis and accumulation of chlorogenic acid in Lonicera japonica flowers
por: Li, Yanqun, et al.
Publicado: (2019)

Arabidopsis floral phytomer development: auxin response relative to biphasic modes of organ initiation
por: Chandler, J. W., et al.
Publicado: (2014)

Geometric Wheat Modeling and Quantitative Plant Architecture Analysis Using Three-Dimensional Phytomers
por: Chang, Wushuai, et al.
Publicado: (2023)

Effects of nitrogen and vapour pressure deficit on phytomer growth and development in a C(4) grass
por: Yang, Fang, et al.
Publicado: (2016)

Chemical quality evaluation of Antrodia cinnamomea fruiting bodies using phytomics similarity index analysis
por: Chung, Cheng-Han, et al.
Publicado: (2015)

Genome-Wide Identification of BAHD Acyltransferases and In vivo Characterization of HQT-like Enzymes Involved in Caffeoylquinic Acid Synthesis in Globe Artichoke
por: Moglia, Andrea, et al.
Publicado: (2016)

YIV-906 enhances nuclear factor of activated T-cells (NFAT) activity of T cells and promotes immune checkpoint blockade antibody action and CAR T-cell activity
por: Lam, Wing, et al.
Publicado: (2023)

Huangqin flavonoid extraction for spinal cord injury in a rat model
por: Zhang, Qian, et al.
Publicado: (2018)

Countably QC-Approximating Posets
por: Mao, Xuxin, et al.
Publicado: (2014)

Replacement of Nitrite in Meat Products by Natural Bioactive Compounds Results in Reduced Exposure to N‐Nitroso Compounds: The PHYTOME Project
por: van Breda, Simone G., et al.
Publicado: (2021)

Disentangling the Heterosis in Biomass Production and Radiation Use Efficiency in Maize: A Phytomer-Based 3D Modelling Approach
por: Liu, Xiang, et al.
Publicado: (2023)

Carpal Tunnel Syndrome: The Role of Occupational Factors Among 906 Workers
por: Ghasemi, Mohammad, et al.
Publicado: (2012)

Protective effects of Huangqin Decoction against ulcerative colitis and associated cancer in mice
por: Chen, Gang, et al.
Publicado: (2016)

QC-LDPC code-based cryptography
por: Baldi, Marco
Publicado: (2014)

ATLAS MICROMEGAS PCB QA/QC
por: Wang, Zihan
Publicado: (2019)

Fantasia in C minor, BWV906 Fifteen two-part inventions ; Fifteen three-part sinfonias (inventions) ; Chromatic fantasia and fugue : in D minor, BWV903 /
por: Bach, Johann Sebastian, 1685-1750
Publicado: (1994)

The seven new QC tools : practical applications for managers /
Publicado: (1984)

906 How Mandatory Public Reporting Undermines Infection Prevention: An Ethnographic Study
por: Szymczak, Julia E., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_m7kqijsc55drded7bo0t7ti2hj