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Pkd1 and Pkd2 Are Required for Normal Placental Development

BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is a common cause of inherited renal failure that results from mutations in PKD1 and PKD2. The disorder is characterized by focal cyst formation that involves somatic mutation of the wild type allele in a large fraction of cysts. Consi...

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Detalles Bibliográficos
Autores principales:	Garcia-Gonzalez, Miguel A., Outeda, Patricia, Zhou, Qin, Zhou, Fang, Menezes, Luis F., Qian, Feng, Huso, David L., Germino, Gregory G., Piontek, Klaus B., Watnick, Terry
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940908/ https://www.ncbi.nlm.nih.gov/pubmed/20862291 http://dx.doi.org/10.1371/journal.pone.0012821

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