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Re-expression of CXCL14, a common target for epigenetic silencing in lung cancer, induces tumor necrosis

Chemokines are important regulators of directional cell migration and tumor metastasis. A genome-wide transcriptome array designed to uncover novel genes silenced by methylation in lung cancer identified the CXC-subfamily of chemokines. Expression of eleven of the sixteen known human CXC-chemokines...

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Detalles Bibliográficos
Autores principales: Tessema, Mathewos, Klinge, Donna M., Yingling, Christin M., Do, Kieu, Van Neste, Leander, Belinsky, Steven A.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2940978/
https://www.ncbi.nlm.nih.gov/pubmed/20562917
http://dx.doi.org/10.1038/onc.2010.255