Characterization of a Family with Rare Deletions in CNTNAP5 and DOCK4 Suggests Novel Risk Loci for Autism and Dyslexia

BACKGROUND: Autism spectrum disorders (ASDs) are characterized by social, communication, and behavioral deficits and complex genetic etiology. A recent study of 517 ASD families implicated DOCK4 by single nucleotide polymorphism (SNP) association and a microdeletion in an affected sibling pair. METH...

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Detalles Bibliográficos
Autores principales: Pagnamenta, Alistair T., Bacchelli, Elena, de Jonge, Maretha V., Mirza, Ghazala, Scerri, Thomas S., Minopoli, Fiorella, Chiocchetti, Andreas, Ludwig, Kerstin U., Hoffmann, Per, Paracchini, Silvia, Lowy, Ernesto, Harold, Denise H., Chapman, Jade A., Klauck, Sabine M., Poustka, Fritz, Houben, Renske H., Staal, Wouter G., Ophoff, Roel A., O'Donovan, Michael C., Williams, Julie, Nöthen, Markus M., Schulte-Körne, Gerd, Deloukas, Panos, Ragoussis, Jiannis, Bailey, Anthony J., Maestrini, Elena, Monaco, Anthony P.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Archival Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941017/
https://www.ncbi.nlm.nih.gov/pubmed/20346443
http://dx.doi.org/10.1016/j.biopsych.2010.02.002

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