Distinct profiles of brain atrophy in frontotemporal lobar degeneration caused by progranulin and tau mutations()

Neural network breakdown is a key issue in neurodegenerative disease, but the mechanisms are poorly understood. Here we investigated patterns of brain atrophy produced by defined molecular lesions in the two common forms of genetically mediated frontotemporal lobar degeneration (FTLD). Nine patients...

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Detalles Bibliográficos
Autores principales: Rohrer, Jonathan D., Ridgway, Gerard R., Modat, Marc, Ourselin, Sebastien, Mead, Simon, Fox, Nick C., Rossor, Martin N., Warren, Jason D.
Formato: Texto
Lenguaje:English
Publicado: Academic Press 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941039/
https://www.ncbi.nlm.nih.gov/pubmed/20045477
http://dx.doi.org/10.1016/j.neuroimage.2009.12.088

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