Transduction of Brain Dopamine Neurons by Adenoviral Vectors Is Modulated by CAR Expression: Rationale for Tropism Modified Vectors in PD Gene Therapy

BACKGROUND: Gene-based therapy is a new paradigm for the treatment of Parkinson disease (PD) and offers considerable promise for precise targeting and flexibility to impact multiple pathobiological processes for which small molecule agents are not available. Some success has been achieved utilizing...

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Detalles Bibliográficos
Autores principales: Lewis, Travis B., Glasgow, Joel N., Glandon, Anya M., Curiel, David T., Standaert, David G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941453/
https://www.ncbi.nlm.nih.gov/pubmed/20862245
http://dx.doi.org/10.1371/journal.pone.0012672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941453/
https://www.ncbi.nlm.nih.gov/pubmed/20862245
http://dx.doi.org/10.1371/journal.pone.0012672

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