Cargando…

Histone deacetylases play distinct roles in telomeric VSG expression site silencing in African trypanosomes

African trypanosomes evade the host immune response through antigenic variation, which is achieved by periodically expressing different variant surface glycoproteins (VSGs). VSG expression is monoallelic such that only one of approximately 15 telomeric VSG expression sites (ESs) is transcribed at a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Qiao-Ping, Kawahara, Taemi, Horn, David
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2941730/
https://www.ncbi.nlm.nih.gov/pubmed/20624217
http://dx.doi.org/10.1111/j.1365-2958.2010.07284.x