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Inhibition of class II histone deacetylases in the spinal cord attenuates inflammatory hyperalgesia
BACKGROUND: Several classes of histone deacetylases (HDACs) are expressed in the spinal cord that is a critical structure of the nociceptive pathway. HDAC-regulated histone acetylation is an important component of chromatin remodeling leading to epigenetic regulation of gene transcription. To unders...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2942827/ https://www.ncbi.nlm.nih.gov/pubmed/20822541 http://dx.doi.org/10.1186/1744-8069-6-51 |