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Loss of Cartilage Structure, Stiffness, and Frictional Properties in Mice Lacking PRG4

OBJECTIVE: To assess the role of the glycoprotein PRG4 in joint lubrication and chondroprotection by measuring friction, stiffness, surface topography, and subsurface histology of the hip joints of Prg4(−/−) and wild-type (WT) mice. METHODS: Friction and elastic modulus were measured in cartilage fr...

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Detalles Bibliográficos
Autores principales:	Coles, Jeffrey M, Zhang, Ling, Blum, Jason J, Warman, Matthew L, Jay, Gregory D, Guilak, Farshid, Zauscher, Stefan
Formato:	Texto
Lenguaje:	English
Publicado:	Wiley Subscription Services, Inc., A Wiley Company 2010
Materias:	Cartilage Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943386/ https://www.ncbi.nlm.nih.gov/pubmed/20191580 http://dx.doi.org/10.1002/art.27436

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