A Key Commitment Step in Erythropoiesis Is Synchronized with the Cell Cycle Clock through Mutual Inhibition between PU.1 and S-Phase Progression

Hematopoietic progenitors undergo differentiation while navigating several cell division cycles, but it is unknown whether these two processes are coupled. We addressed this question by studying erythropoiesis in mouse fetal liver in vivo. We found that the initial upregulation of cell surface CD71...

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Detalles Bibliográficos
Autores principales: Pop, Ramona, Shearstone, Jeffrey R., Shen, Qichang, Liu, Ying, Hallstrom, Kelly, Koulnis, Miroslav, Gribnau, Joost, Socolovsky, Merav
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943437/
https://www.ncbi.nlm.nih.gov/pubmed/20877475
http://dx.doi.org/10.1371/journal.pbio.1000484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943437/
https://www.ncbi.nlm.nih.gov/pubmed/20877475
http://dx.doi.org/10.1371/journal.pbio.1000484

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