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A Genetic Association Study of Serum Acute-Phase C-Reactive Protein Levels in Rheumatoid Arthritis: Implications for Clinical Interpretation

BACKGROUND: The acute-phase increase in serum C-reactive protein (CRP) is used to diagnose and monitor infectious and inflammatory diseases. Little is known about the influence of genetics on acute-phase CRP, particularly in patients with chronic inflammation. METHODS AND FINDINGS: We studied two in...

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Detalles Bibliográficos
Autores principales: Rhodes, Benjamin, Merriman, Marilyn E., Harrison, Andrew, Nissen, Michael J., Smith, Malcolm, Stamp, Lisa, Steer, Sophia, Merriman, Tony R., Vyse, Timothy J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943443/
https://www.ncbi.nlm.nih.gov/pubmed/20877716
http://dx.doi.org/10.1371/journal.pmed.1000341