Cargando…

Cytosolic Phospholipase A2 and Lysophospholipids in Tumor Angiogenesis

BACKGROUND: Lung cancer and glioblastoma multiforme are highly angiogenic and, despite advances in treatment, remain resistant to therapy. Cytosolic phospholipase A2 (cPLA(2)) activation contributes to treatment resistance through transduction of prosurvival signals. We investigated cPLA(2) as a nov...

Descripción completa

Detalles Bibliográficos
Autores principales:	Linkous, Amanda G., Yazlovitskaya, Eugenia M., Hallahan, Dennis E.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943523/ https://www.ncbi.nlm.nih.gov/pubmed/20729478 http://dx.doi.org/10.1093/jnci/djq290

Ejemplares similares

Autotaxin and LPA Receptors Represent Potential Molecular Targets for the Radiosensitization of Murine Glioma through Effects on Tumor Vasculature
por: Schleicher, Stephen M., et al.
Publicado: (2011)

Cytosolic PhospholipaseA2 Inhibition with PLA-695 Radiosensitizes Tumors in Lung Cancer Animal Models
por: Thotala, Dinesh, et al.
Publicado: (2013)

Discrete Role for Cytosolic Phospholipase A(2)α in Platelets: Studies Using Single and Double Mutant Mice of Cytosolic and Group IIA Secretory Phospholipase A(2)
por: Wong, Dennis A., et al.
Publicado: (2002)

Synthesis of Lysophospholipids
por: D’Arrigo, Paola, et al.
Publicado: (2010)

The hemolytic and cytolytic activities of Serratia marcescens phospholipase A (PhlA) depend on lysophospholipid production by PhlA
por: Shimuta, Ken, et al.
Publicado: (2009)

Lysophospholipids in laboratory medicine
por: YATOMI, Yutaka, et al.
Publicado: (2018)

Cytosolic Phospholipase A2 Modulates TLR2 Signaling in Synoviocytes
por: Sommerfelt, Randi M., et al.
Publicado: (2015)

Lysophospholipid Signaling in the Epithelial Ovarian Cancer Tumor Microenvironment
por: Xu, Yan
Publicado: (2018)

Emerging Role of Phospholipase-Derived Cleavage Products in Regulating Eosinophil Activity: Focus on Lysophospholipids, Polyunsaturated Fatty Acids and Eicosanoids
por: Knuplez, Eva, et al.
Publicado: (2021)

Highly Potent 2-Oxoester Inhibitors of Cytosolic Phospholipase A(2) (GIVA cPLA(2))
por: Psarra, Anastasia, et al.
Publicado: (2018)

Genotypic Variation in Wheat Flour Lysophospholipids
por: Liu, Lei, et al.
Publicado: (2017)

Cyclooxygenase-2 and Cytosolic Phospholipase A2 Are Overexpressed in Mucinous Pancreatic Cysts
por: Mensah, Elsie T., et al.
Publicado: (2019)

Correction to “Highly Potent 2-Oxoester Inhibitors of Cytosolic Phospholipase A(2) (GIVA cPLA(2))”
por: Psarra, Anastasia, et al.
Publicado: (2019)

Lysophospholipids Facilitate COPII Vesicle Formation
por: Melero, Alejandro, et al.
Publicado: (2018)

2-Oxoesters: A Novel Class of Potent and Selective Inhibitors of Cytosolic Group IVA Phospholipase A(2)
por: Kokotou, Maroula G., et al.
Publicado: (2017)

Role of Phosphorylation Sites and the C2 Domain in Regulation of Cytosolic Phospholipase A(2)
por: Gijón, Miguel A., et al.
Publicado: (1999)

Prognostic significance of cytosolic phospholipase A2 expression in patients with colorectal cancer
por: Yoo, Young Sun, et al.
Publicado: (2011)

Cytosolic phospholipase A2 regulation in the hibernating thirteen-lined ground squirrel
por: Woods, Ashley K., et al.
Publicado: (2007)

Cytosolic group IVA phospholipase A2 inhibitors, AVX001 and AVX002, ameliorate collagen-induced arthritis
por: Feuerherm, A. J., et al.
Publicado: (2019)

Pharmacophore-based discovery of a novel cytosolic phospholipase A(2)α inhibitor
por: Noha, Stefan M., et al.
Publicado: (2012)

Cytosolic Phospholipase A(2)α–deficient Mice Are Resistant to Collagen-induced Arthritis
por: Hegen, Martin, et al.
Publicado: (2003)

Functions and mechanisms of cytosolic phospholipase A(2) in central nervous system trauma
por: Zhang, Hao-Jie, et al.
Publicado: (2022)

Impacts of Cytosolic Phospholipase A2, 15-Prostaglandin Dehydrogenase, and Cyclooxygenase-2 Expressions on Tumor Progression in Colorectal Cancer
por: Lim, Sung Chul, et al.
Publicado: (2010)

Serum lysophospholipid levels are altered in dyslipidemic hamsters
por: Suárez-García, Susana, et al.
Publicado: (2017)

Cytosolic phospholipase A(2)α–deficient mice are resistant to experimental autoimmune encephalomyelitis
por: Marusic, Suzana, et al.
Publicado: (2005)

Structural basis of phosphatidylcholine recognition by the C2–domain of cytosolic phospholipase A(2)α
por: Hirano, Yoshinori, et al.
Publicado: (2019)

Inhibition of Cytosolic Phospholipase A2α Induces Apoptosis in Multiple Myeloma Cells
por: Mahammad, Nur, et al.
Publicado: (2021)

Lysophospholipids in the limelight: autotaxin takes center stage
por: Moolenaar, Wouter H.
Publicado: (2002)

Analysis of glycero-lysophospholipids in gastric cancerous ascites
por: Emoto, Shigenobu, et al.
Publicado: (2017)

Cytosolic Phospholipase A2 Regulates TNF-Induced Production of Joint Destructive Effectors in Synoviocytes
por: Sommerfelt, Randi M., et al.
Publicado: (2013)

Regulatory role of cytosolic phospholipase A(2) alpha in the induction of CD40 in microglia
por: Malada-Edelstein, Yafa Fetfet, et al.
Publicado: (2017)

Alteration in Lysophospholipids and Converting Enzymes in Glaucomatous Optic Nerves
por: Milbeck, Sasha M., et al.
Publicado: (2020)

Correction: Structural basis of phosphatidylcholine recognition by the C2-Domain of cytosolic phospholipase A(2)α
por: Hirano, Yoshinori, et al.
Publicado: (2021)

The Step Further to Understand the Role of Cytosolic Phospholipase A(2) Alpha and Group X Secretory Phospholipase A(2) in Allergic Inflammation: Pilot Study
por: Pniewska, Ewa, et al.
Publicado: (2014)

Dietary Supplementation of Lysophospholipids Affects Feed Digestion in Lambs
por: Huo, Qin, et al.
Publicado: (2019)

Lysophospholipids: A Potential Drug Candidates for Neurodegenerative Disorders
por: Karaki, Tatsuya, et al.
Publicado: (2022)

Cytosolic Phospholipase A(2) Protein as a Novel Therapeutic Target for Spinal Cord Injury
por: Liu, Nai-Kui, et al.
Publicado: (2014)

Unique targeting of cytosolic phospholipase A(2) to plasma membranes mediated by the NADPH oxidase in phagocytes
por: Shmelzer, Zeev, et al.
Publicado: (2003)

Predominant Role of Cytosolic Phospholipase A(2)α in Dioxin-induced Neonatal Hydronephrosis in Mice
por: Yoshioka, Wataru, et al.
Publicado: (2014)

Study of the Role of Cytosolic Phospholipase A(2) Alpha in Eicosanoid Generation and Thymocyte Maturation in the Thymus
por: Rousseau, Matthieu, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_8eand8jjll4jaq5ksm817b91q7