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Shared dependence on TOX for development of lymphoid tissue inducer cell and NK cell lineages
Thymocyte selection-associated HMG box factor (TOX) is a DNA-binding factor required for development of CD4 T cells, natural killer T cells, and T regulatory cells. Here we document that both NK cell development and lymphoid tissue organogenesis are inhibited in the absence of TOX. We find that deve...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943551/ https://www.ncbi.nlm.nih.gov/pubmed/20818394 http://dx.doi.org/10.1038/ni.1930 |