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Identification of β-catenin binding regions in colon cancer cells using ChIP-Seq

Deregulation of the Wnt/β-catenin signaling pathway is a hallmark of colon cancer. Mutations in the adenomatous polyposis coli (APC) gene occur in the vast majority of colorectal cancers and are an initiating event in cellular transformation. Cells harboring mutant APC contain elevated levels of the...

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Detalles Bibliográficos
Autores principales:	Bottomly, Daniel, Kyler, Sydney L., McWeeney, Shannon K., Yochum, Gregory S.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943592/ https://www.ncbi.nlm.nih.gov/pubmed/20460455 http://dx.doi.org/10.1093/nar/gkq363

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