Cargando…

siRNAs compete with miRNAs for methylation by HEN1 in Arabidopsis

Plant microRNAs (miRNAs) and small interfering RNAs (siRNAs) bear a 2′-O-methyl group on the 3′-terminal nucleotide. This methyl group is post-synthetically added by the methyltransferase protein HEN1 and protects small RNAs from enzymatic activities that target the 3′-OH. A mutagenesis screen for s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Bin, Bi, Liu, Zhai, Jixian, Agarwal, Manu, Li, Shengben, Wu, Qingfa, Ding, Shou-Wei, Meyers, Blake C., Vaucheret, Hervé, Chen, Xuemei
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2010
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943618/ https://www.ncbi.nlm.nih.gov/pubmed/20448024 http://dx.doi.org/10.1093/nar/gkq348

Ejemplares similares

Genome-wide analysis of single non-templated nucleotides in plant endogenous siRNAs and miRNAs
por: Wang, Feng, et al.
Publicado: (2016)

Comparative analysis of non-autonomous effects of tasiRNAs and miRNAs in Arabidopsis thaliana
por: de Felippes, Felipe Fenselau, et al.
Publicado: (2011)

The miRNA pathway limits AGO1 availability during siRNA-mediated PTGS defense against exogenous RNA
por: Martínez de Alba, Angel Emilio, et al.
Publicado: (2011)

Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues
por: Castellano, Leandro, et al.
Publicado: (2013)

miRNAs trigger widespread epigenetically-activated siRNAs from transposons in Arabidopsis
por: Creasey, K.M., et al.
Publicado: (2014)

Gene structures and processing of Arabidopsis thaliana HYL1-dependent pri-miRNAs
por: Szarzynska, Bogna, et al.
Publicado: (2009)

Genetic framework for flowering-time regulation by ambient temperature-responsive miRNAs in Arabidopsis
por: Lee, Hanna, et al.
Publicado: (2010)

Adenylation of plant miRNAs
por: Lu, Shanfa, et al.
Publicado: (2009)

In plants, decapping prevents RDR6-dependent production of small interfering RNAs from endogenous mRNAs
por: Martínez de Alba, Angel Emilio, et al.
Publicado: (2015)

siRNAs targeted to certain polyadenylation sites promote specific, RISC-independent degradation of messenger RNAs
por: Vickers, Timothy A., et al.
Publicado: (2012)

Inhibition of MDR1 expression with altritol-modified siRNAs
por: Fisher, Michael, et al.
Publicado: (2007)

RNA polymerase V-dependent small RNAs in Arabidopsis originate from small, intergenic loci including most SINE repeats
por: Lee, Tzuu-fen, et al.
Publicado: (2012)

GW body disassembly triggered by siRNAs independently of their silencing activity
por: Serman, A., et al.
Publicado: (2007)

A role for human Dicer in pre-RISC loading of siRNAs
por: Sakurai, Kumi, et al.
Publicado: (2011)

Tissue-dependent paired expression of miRNAs
por: Ro, Seungil, et al.
Publicado: (2007)

Improved specificity of gene silencing by siRNAs containing unlocked nucleobase analogs
por: Vaish, Narendra, et al.
Publicado: (2011)

Biogenesis of phased siRNAs on membrane-bound polysomes in Arabidopsis
por: Li, Shengben, et al.
Publicado: (2016)

Characterization and expression profiles of miRNAs in rice seeds
por: Xue, Liang-Jiao, et al.
Publicado: (2009)

RNA cleavage products generated by antisense oligonucleotides and siRNAs are processed by the RNA surveillance machinery
por: Lima, Walt F., et al.
Publicado: (2016)

Human box C/D snoRNAs with miRNA like functions: expanding the range of regulatory RNAs
por: Brameier, Markus, et al.
Publicado: (2011)

Inhibition of HIV-1 by multiple siRNAs expressed from a single microRNA polycistron
por: Liu, Ying Poi, et al.
Publicado: (2008)

Controlling activation of the RNA-dependent protein kinase by siRNAs using site-specific chemical modification
por: Puthenveetil, Sujiet, et al.
Publicado: (2006)

Delivery of chemo-sensitizing siRNAs to HER2(+)-breast cancer cells using RNA aptamers
por: Thiel, Kristina W., et al.
Publicado: (2012)

Primary and secondary siRNA synthesis triggered by RNAs from food bacteria in the ciliate Paramecium tetraurelia
por: Carradec, Quentin, et al.
Publicado: (2015)

Identification and analysis of seven H(2)O(2)-responsive miRNAs and 32 new miRNAs in the seedlings of rice (Oryza sativa L. ssp. indica)
por: Li, Tian, et al.
Publicado: (2011)

Differences in silencing of mismatched targets by sliced versus diced siRNAs
por: Sun, Guihua, et al.
Publicado: (2018)

SKI2 mediates degradation of RISC 5′-cleavage fragments and prevents secondary siRNA production from miRNA targets in Arabidopsis
por: Branscheid, Anja, et al.
Publicado: (2015)

Sequencing of RDR6-dependent double-stranded RNAs reveals novel features of plant siRNA biogenesis
por: Rajeswaran, Rajendran, et al.
Publicado: (2012)

Dual functional BAFF receptor aptamers inhibit ligand-induced proliferation and deliver siRNAs to NHL cells
por: Zhou, Jiehua, et al.
Publicado: (2013)

Anopheles gambiae miRNAs as actors of defence reaction against Plasmodium invasion
por: Winter, Flore, et al.
Publicado: (2007)

Extensive terminal and asymmetric processing of small RNAs from rRNAs, snoRNAs, snRNAs, and tRNAs
por: Li, Zhihua, et al.
Publicado: (2012)

Profiling of T helper cell-derived small RNAs reveals unique antisense transcripts and differential association of miRNAs with argonaute proteins 1 and 2
por: Polikepahad, Sumanth, et al.
Publicado: (2013)

Identification of human miRNA precursors that resemble box C/D snoRNAs
por: Ono, Motoharu, et al.
Publicado: (2011)

Strand selective generation of endo-siRNAs from the Na/phosphate transporter gene Slc34a1 in murine tissues
por: Carlile, Mark, et al.
Publicado: (2009)

Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5′-terminal phosphorylation both in vitro and in vivo
por: Kenski, Denise M., et al.
Publicado: (2010)

In vivo screening of modified siRNAs for non-specific antiviral effect in a small fish model: number and localization in the strands are important
por: Schyth, Brian Dall, et al.
Publicado: (2012)

Functional features defining the efficacy of cholesterol-conjugated, self-deliverable, chemically modified siRNAs
por: Shmushkovich, Taisia, et al.
Publicado: (2018)

A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
por: Bramsen, Jesper B., et al.
Publicado: (2009)

Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells
por: Zhou, Jiehua, et al.
Publicado: (2009)

Plant U13 orthologues and orphan snoRNAs identified by RNomics of RNA from Arabidopsis nucleoli
por: Kim, Sang Hyon, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_qsvn39kui5odnfu0ouk3rom2n3