Microarray-based STR genotyping using RecA-mediated ligation

We describe a novel assay capable of accurately determining the length of short tandem repeat (STR) alleles. STR genotyping is achieved utilizing RecA-mediated ligation (RML), which combines the high fidelity of RecA-mediated homology searching with allele-specific ligation. RecA catalyzes the pairi...

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Detalles Bibliográficos
Autores principales: Herrmann, David, Rose, Emily, Müller, Uwe, Wagner, Robert
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943619/
https://www.ncbi.nlm.nih.gov/pubmed/20682559
http://dx.doi.org/10.1093/nar/gkq657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943619/
https://www.ncbi.nlm.nih.gov/pubmed/20682559
http://dx.doi.org/10.1093/nar/gkq657

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